Reactor-Ready™ Lab Reactor

Reactor-Ready Core and Components

The reactor Ready Core includes all of the following components:

• Stand with base, drip tray, support rods, bosses and all clamps
• Glass Reaction Vessel Lid
• Vessel FEP O-ring seal and PTFE Collar
• HDPE Drip Tray
• Vessel to Manifold Insulated Hoses with Quick-Release Connections
• Lower Inlet Manifold + Drain

• Upper Outlet Manifold + Vent
• PTFE Stirrer Guide and Coupling
• Stainless steel Stirrer Drive Coupling
• Two stainless steel Vessel Support Collars
• Locking Rod for Support Rod Bosses

Hoses to connect the Reactor-Ready framework to a thermoregulator are NOT included. You will require hoses with an M24 x 1.5 female connection or appropriate adapters.

DN100 5 neck Glass Lid fits all Vessel sizes

• Supplied as part of the Reactor-Ready Core
• DN100 lid with 5 x Rodaviss, grease-free, safety joints.
• All Rodaviss joints are interchangeable with ordinary A, B and C length conical joints.
• Rodaviss A length joints available if required

How to order Reactor-Ready Lab Reactor

1. Select the Reactor-Ready Core.
2. Choose the Vessel Kit or Kits you require by selecting the vessel volume and style.
3. Select the overhead stirrer you need.
4. If you need a thermoregulator, hoses, hose adapters, thermofluid or accessory glassware, then select from the accessory list.
5. If you need automation add AVA Control Software and Data Hub.

Patented vessel clamp allows rapid vessel exchange without tools

• Unique clamp design allows vessel to be supported and clamped by a single operator in less than a minute
• Use the same clamp to hold all vessel sizes; plus the vessels remain supported even when the clamp is unlocked

Vessel Support Collar aids vessel loading

• Reactor-Ready uses an innovative support collar fitted to the neck of each vessel, which allows the vessels to be swapped in and out of the Reactor-Reactor core like a cartridge
• The stainless steel collar locks securely into the support plate on the framework and allows the vessel to remain supported, even when not clamped
• Vessel exchange is tool free and can easily be undertaken by one person

Unique Self aligning Stirrer Coupling saves time when changing Vessels

• Patented drop-in stirrer coupling engages easily without the need for tools
• Simply lower the stirrer coupling to engage with the stirrer guide below
• The stainless steel stirrer coupling will fit in any standard stirrer chuck
• The non-slip design ensures powerful stirring up to 500rpm, or 800rpm for short periods (subject to motor selected)

Choice of PTFE stirring shafts

• Reactor-Ready is offered with a choice of PTFE Stirring Shafts: Anchor, Retreat Curve and Turbine or Propeller styles
• PTFE Anchor Stirring Shaft is included with all standard reaction vessel kits
• PTFE Turbine Stirring Shaft is included with all process reaction vessel kits

I-beam Support allows the Stirring Motor to be positioned with ease

• I-beam allows the stirrer drive to be raised or lowered without needing to remount the stirrer
• Adjustable safety stop collars located below the I-beam allow the user to lower the stirrer motor to a set position for ease of operation and safety
• Reactor-Ready accepts all leading brands of motor or air-powered overhead stirrer with support rods up to 16 mm in diameter

Whip-free stirrer guide

• The Reactor-Ready’s PTFE stirrer guide screws directly on to the glass lid and features a unique extended support which provides whip-free agitation even at high speeds
• The stirrer guide is chemically inert, gas tight and suitable for work under vacuum

Quick Release PEEK Hose Couplings

• Operates over the temperature range -70˚C to +230˚C
• Quick release, screwthread design allows rapid exchange of vessels without the use of tools
• Simply tighten by hand for a leak tight seal
• PEEK with Viton O-rings ensures all wetted parts are chemically resistant
• Lightweight, metal free design prevents chipping and minimises strain on the glass fitting
• All hoses have a 12mm ID, maximising thermofluid flow and heating/cooling performance
• Low thermal conductivity of PEEK reduces frosting when cooling

Hose Manifolds allow easy Thermofluid drain down

• The inlet and outlet hoses from the Reactor-Ready vessel connect to manifolds attached to the support rod
• These manifolds serve two important functions:
  1. Supports the hose running from the vessel, thereby eliminating stress on the glass sidearm.
  2. Allows thermofluid drain down which provides a quick and clean method of removing the thermofluid from the vessel jacket when changing vessels
• By opening the venting valve on the (upper) outlet manifold, thermofluid drains from the vessel back to the thermoregulator under gravity
• Opening the drain tap on the (lower) inlet manifold allows drainage to an external reservoir

Scaling up crystallisation: Insights from CatSci and BlazeMetrics

In this technical webinar our hosts discuss the importance of developing a good crystallisation process for APIs, and how process analytical technologies (PAT) can enhance understanding of the process. 

Dr Scott shows case studies designing the crystallisation processes of two compounds, to determine the most stable form for further process development.

Dr Callahan explains how advanced technologies, such as the Blaze probe increase process understanding which can mitigate risks during process development and help optimise crystallisation processes.

Webinar: Reactor-Ready Recap: Scaling up Safely and Efficiently

Using highlights from previous webinars, this webinar will focus on the Reactor-Ready jacketed lab reactor, its benefits, and practical applications. Key topics include: the advantages of jacketed lab reactors, considerations when scaling up including temperature and agitation method, and different vessel types. We will also show how easy it is to swap between vessels, enabling quick scalability.

Webinar: How to optimise mixing within your jacketed reaction vessels

In this webinar we will discuss factors to consider which apply when scaling chemical reactions up or scaling down to predict or reproduce conditions observed in the larger scale manufacturing environment.

Blog: Understanding and overcoming the challenges in chemical synthesis at a global CDMO

Andrew Kennedy and Jono West from Sai Life Sciences are interviewed about the work they do and how they utilise Radleys equipment in order to understand and overcome chemical synthesis challenges.