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Scaling up exothermic additions in the lab
Are you currently using beakers, dropping funnels and syringes to dose your reactions with a liquid reagent? How long do you stand around tweaking your drip rate? What if you had software that could control those liquid additions, with the benefits of data logging, feedback loops and safety overrides.
Why Crystallise? Introduction to techniques and tips on equipment setup
In this webinar we will discuss the benefits of crystallisation as a tool for product isolation, versus other common techniques.
We will look at the methods of performing crystallisations used by chemists, with examples, including cooling, anti-solvent, pH adjustment and reactive crystallisations. There will be discussion of the Meta Stable Zone (MSZ) and use of phase diagrams.
Finally, we will discuss what equipment is most effective for performing crystallisations along with some tips to improve your crystallisation processes.
Tips and tools to aid your reaction optimisation
Reaction optimisation is a key component across the pharmaceutical development cycle. From early-stage small library production to full scale manufacturing, optimising a reaction for the desired outcome can be a difficult and time-consuming exercise.
In this short webinar we will discuss these parameters and look at some customer examples to highlight the points raised and how these challenges were addressed.
Consistent Scaling Up
Scaling up chemical reactions can present a number of challenges with respect to efficient mixing, mass transfer, controlling exothermic reactions, heat transfer and reaction kinetics.
In this webinar we discussed some simple guidelines which apply when scaling chemical reactions up or scaling down to predict or reproduce conditions observed in the larger scale manufacturing environment.
Introducing the Radleys Reactor-Ready Filter Lab Reactor
Temperature controlled, stirred and contained filtrations – Radleys Reactor-Ready Filter Lab Reactor for crystallisations, reaction work-ups and product isolation
In this webinar we will explore the Radleys range of Reactor-Ready filter vessels, demonstrate how to assemble and use the filter reactor as well as discuss potential applications.
Increasing efficiency in contract synthesis
Efficiency, quality and flexibility in Contract Synthesis – Is your lab achieving this?
Contract synthesis has challenges to deliver the right material, in the right time in a fast-changing project lifecycle. In this short webinar we will discuss in more detail what these challenges are and how to solve them.
Accelerate your OPRD with Mya 4
Accelerate your Process Research and Development with a flexible reaction station. In this webinar we’ll show you how to improve reproducibility and eliminate time-wasted manually recording results with automated data logging.
Mya 4 can be set up quickly: benefitting from flexible and versatile configurations, easily meeting the needs of different applications and projects.
How to keep your reactor, ready
Regular maintenance of your jacketed lab reactor will ensure that you get the most out of your equipment and prolong its lifetime. In this webinar we will cover how to perform routine checks and maintenance on your Jacketed Lab Reactor to ensure that you achieve efficient mixing, accurate temperature control and good sealing when performing your chemistry.
Are you running your overnight reactions safely?
Are you running your overnight reactions unsafely? Lab control software can help you perform safe and efficient unattended reactions
In this webinar we will discuss how reactions can be data logged as well as safety feedback loops put in place to ensure that reactions can be left unattended overnight or longer by using lab control software.
How to achieve efficient temperature control when using Jacketed Lab Reactors
When it comes to chemical reactions in both R&D and production processes, achieving the right temperature is crucial. In this webinar we will be joined by Dr Paddy Delaney from Huber to discuss the factors that influence temperature control when using jacketed lab reactors as well as advice on how to improve the performance of your system.
Benefits of overhead stirring on a small scale
Join us to discuss the benefits of overhead stirring on a small scale:
Beyond the White Paper - How Purolite improved their process development with Mya 4
Based on a white paper on the same topic, Dr Patrick Gilbert from Purolite explains how his R&D group greatly improved their small-scale Process development and DoE work.
Data-led, this case study presentation shows you how this was achieved.
Why you don't need a bigger rotary evaporator - just add continuous evaporation
Learn how the new Heidolph Distimatic Pro automates rotary evaporation processes on industrial scale (>20 L), completely eliminating the need for users to manually refill and empty flasks, for complete automated evaporation.
In this webinar Ravi Hosein (Radleys) and Jurgen Heyder (Heidolph) will show you how the new Distimatic Pro and Reactor-Ready Pilot work in tandem for automated operation.
Why you might be doing your small-scale process development wrong
Are you using round bottom flasks with heating only equipment for your small-scale process development chemistry? Do you find these experiments don’t scale up as well as you would like?
Let’s talk about what’s wrong with this traditional set up and what you can do to improve it.
The benefits of Jacketed Lab Reactors and considerations when choosing a system
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When purchasing a jacketed lab reactor setup for scaling up your process, there are many considerations to be made.
In this webinar we cover the fundamental points of specifying the right reactor and ancillary devices to ensure that you get the optimal performance of your jacketed lab reactor system for scale-up and process development.
How to improve rotary evaporation processes – Radleys, VACUUBRAND & Heidolph
We discuss the importance of vacuum control in common lab applications, covering the different types of vacuum pumps used in the lab and best practices for using and maintaining them. We also focus on rotary evaporation and how vacuum affects bumping and foaming of products, ways to mitigate these, plus tips to make your evaporation processes more efficient.
Stirring viscous reactions - save space and time with Tornado
Do you require mechanical stirring on small scale reactions? E.g. viscous materials, heterogeneous mixtures, fragile solids?
Join us to see the Tornado Overhead Stirring System in action. Save time and space for the overhead stirring of multiple reactions in round bottom flasks.
Reaction system design – Learn from the experts
In this webinar we look at some considerations when designing a jacketed lab reactor system and their implications.
We then follow on with some bespoke design options available for our jacketed reactors, where we review a variety of subjects including reactor geometry, thermal fluid connections, lid port design, drain valves and more illustrated with some examples of custom systems we have done for users.
Streamline your process development toolkit
When choosing the kit you will use for your Process R&D chemistry, there are many considerations to be made.
If you’re currently using hotplates, ice baths and jacketed reactors for your small-scale Process R&D chemistry, how could you consolidate this work with a single piece of equipment?
In this webinar we discuss the most common needs for process chemistry and introduce the Mya 4 Reaction station for screening reactions to small scale Design of Experiment.
Reactor Customisation options and Glassblowing capability
Mark Radley shows you inside our glass blowing workshop for a live demonstration then on to a technical discussion on the bespoke design options for all Radleys reactors.
*please note that due to a technical interruption the start is missing from the recording.
Best practices and how to get the most out of your Rotary Evaporator
Rotary Evaporation principles explained
In this webinar you’ll learn about the principles behind rotary evaporation, the basics of using a rotary evaporator, how to make your evaporations more efficient and also how to maintain your rotary evaporator to increase its life span.
Unleash your humble hotplate – it can do so much more than you think
Are you making the most of your hotplate?
Louisa Quegan and Keren Abecassis share their chemistry lab hacks: showing you a range of tools you might not know about.
From 1 position to 45 on a single hotplate – with working volumes between 0.5 ml and 2.5 L. Lou and Keren discuss their personal experience in the lab using traditional methods vs. this range of tools.
Automation of chemical processes and remote data-logging in R&D laboratories
This webinar will be a case study of a scale-up group, using an automated addition to control an exothermic reaction, and the use of safety feedback loops to pause and restart the addition based on process temperature. At this time of social distancing in our laboratories when we need to minimise the number of people in the lab, automation and data-logging can help.
Introducing - Productivity and Parallel Chemistry tools
An introduction to the range of productivity and parallel chemistry tools in the Radleys range with a live demonstration and hands on approach.
The Heidolph Distimatic – automating your rotary evaporator for continuous, unattended solvent removal
An in depth look at the Heidolph Distimatic, which automates rotary evaporators to remove bottlenecks to the solvent removal process. Including a full hands-on demonstration of the equipment.
Hotplates & add-ons to make your chemistry lab a safer and cleaner place to work
With safer, cleaner and greener working practices high on the agenda for lab managers and user’s, we talk you through simple but effective changes you can make to improve the way you do your chemistry.
Productivity and Parallel Chemistry tools - Carousel 6 and Carousel 12 in detail
A hands-on walk through the Carousel 6 and 12 in detail. We look at all the tools and accessories in this range and then run through the operation and setup.
We include information on using a Carousel, how to dry the system, running efficient reflux experiments and any necessary maintenance.
Live hands-on demonstration of the Mya 4 Reaction Station
Introduction to the Mya 4 Reaction Station range from Radleys – hands-on live demonstration and Q&A. Mya 4 is highly flexible reaction station with 4 independent zones for accurate temperature control and reaction optimisation.
Mya 4 PC Control Software tour of the key features and making the most of your software
Watch ‘Introducing – Mya Reaction Station’ before you watch this.
Once you’ve seen a demonstration of the Mya 4 Reaction Station, watch this to learn differences between the Mya 4 Control Pad and the PC control software and which one would suit your application best.
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