What vacuum level can be achieved in Radleys jacketed lab reactors? The vacuum obtained for a whole reaction system is typically approximately 10-50 mbar, although even better vacuum can be achieved – we have observed around 3-5 mbar under stationary test conditions in Reactor-Ready. The vacuum level that is obtained in a specific reaction system will depend on various factors, including: The type of reaction system – Reactor-Ready, Reactor-Ready Duo, Reactor-Ready Pilot and Lara have an advanced design with better sealing than other reaction systems, so particularly good vacuum can be achieved Whether glass cone stoppers (optional accessories) are used to plug any unused lid ports (required for the best possible vacuum), rather than Rodaviss sealing caps The particular vacuum pump used (considering the pump’s ultimate vacuum and speed etc.); also note that when a vacuum pump/tubing is new, you may need to run the vacuum for some hours before the best vacuum levels can be achieved Whether there is any water (or other substance) in the system – vacuum can cause this to evaporate, increasing the pressure The condition of all the seals/O-rings and piston – these are consumable parts and should be checked and replaced if required The condition and position of other components such as stirrer guide, stirrer shaft and probes Whether all joints are clean, assembled correctly and tight Whether all valves are closed properly Whether the vessel/lid clamp is tight enough Whether vacuum grease (silicone grease) is used on joints The stirring taking place (speed/viscosity etc.) The temperature within the vessel The reaction taking place within the vessel For details of our vacuum testing procedure, please refer to our technical bulletin ‘TB 102 Reactor-Ready vacuum and pressure testing’, available to download here.